Hydrochloric Acid → 4-Decyloxybenzyl alcohol

HRID 1703073

Reaktionsgleichung

Reaktionsgleichung von HRID 1703073
B.[CH2:2]([O:12][C:13]1[CH:21]=[CH:20][C:16]([C:17](O)=[O:18])=[CH:15][CH:14]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].Cl>O1CCCC1.O>[CH2:2]([O:12][C:13]1[CH:14]=[CH:15][C:16]([CH2:17][OH:18])=[CH:20][CH:21]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

Komponenten

6

Edukt 3

HCID 313Hydrochloric AcidHCID 6331BoraneHCID 1385274-(Decyloxy)benzoic acid

Produkt 1

HCID 130796524-Decyloxybenzyl alcohol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 8028TetrahydrofuranLösungsmittel2×

Versuchsvorschrift

To 100 ml. of 1.0 M borane in tetrahydrofuran cooled in an ice bath under nitrogen is added dropwise, 27.8 g. of p-decyloxybenzoic acid in 300 ml. of tetrahydrofuran over a period of 45 minutes. The mixture is stirred at room temperature for 6 hours and poured onto ice, diluted with water and 10 ml. of concentrated hydrochloric acid. The mixture is filtered and the solid washed with water to give white crystals. Recrystallization from ethanol gives white plates, m.p. 57.5°-59° C.

Aufarbeitung

  1. additionis added dropwise
  2. additionpoured onto ice
  3. filtrationThe mixture is filtered
  4. washthe solid washed with water
  5. customto give white crystals
  6. customRecrystallization from ethanol
  7. customgives white plates, m.p. 57.5°-59° C.

Quellen und Nachweise

ORD-Eintrag
ord-1886cca7e74b47babd18d00a53db5053
Quelldatensatz
uspto-grants-1982_09
Patentnummer
US04350822

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