Butylbenzene → 4-Butyl-2'-fluorobenzophenone

HRID 1703581

Reaktionsgleichung

Reaktionsgleichung von HRID 1703581
[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].[Cl-].[Al+3].[Cl-].[Cl-].[CH2:15]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH2:16][CH2:17][CH3:18]>C(=S)=S>[CH2:15]([C:19]1[CH:24]=[CH:23][C:22]([C:4]([C:3]2[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=2[F:1])=[O:5])=[CH:21][CH:20]=1)[CH2:16][CH2:17][CH3:18]

Komponenten

5

Edukt 3

HCID 7705ButylbenzeneHCID 98082-Fluorobenzoyl chlorideHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 473524-Butyl-2'-fluorobenzophenoneAusbeute 62,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6348Carbon DisulfideLösungsmittel

Versuchsvorschrift

A 3.16 g (0.02 mole) of 2-fluoro benzoic acid chloride was dissolved in 30 ml of carbon disulfide and then, 4.0 g (0.03 mole) of anhydrous aluminum chloride was added to the solution. A 2.68 g (0.02 mole) of n-butyl benzene was further added to the mixture with stirring, and the reaction was carried out at room temperature for 18 hours. In accordance with the process of Example 1, the reaction mixture was treated to obtain 3.2 g of 4-n-butyl-2'-fluorobenzophenone having a boiling point of 180° to 190° C./5 mmHg. (yield of 62.5%).

Aufarbeitung

  1. additionIn accordance with the process of Example 1, the reaction mixture was treated

Quellen und Nachweise

ORD-Eintrag
ord-badff87eff144b81a28d22b3f4099785
Quelldatensatz
uspto-grants-1978_11
Patentnummer
US04124726

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