HCID 20337447, Verbindung → HCID 86737026, Verbindung
Reaktionsgleichung
[OH:1][C:2]1[C:17]([CH:18]([CH3:28])[CH2:19][CH2:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:16][C:5]2[O:6][C:7]([CH3:15])([CH3:14])[C:8]3[CH2:13][CH2:12][CH2:11][CH2:10][C:9]=3[C:4]=2[CH:3]=1>[Pd].C(O)C>[OH:1][C:2]1[C:17]([CH:18]([CH3:28])[CH2:19][CH2:20][CH2:21][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[CH:16][C:5]2[O:6][C:7]([CH3:14])([CH3:15])[C@@H:8]3[CH2:13][CH2:12][CH2:11][CH2:10][C@@H:9]3[C:4]=2[CH:3]=1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
To a solution of 1.0 g. of dl-7,8,9,10-tetrahydro-2-hydroxy-6,6-dimethyl-3-(1-methyl-4-phenylbutyl)-6H-dibenzo[b,d]pyran in 75 ml. of ethanol is added 200 mg. of 5% palladium-on-carbon catalyst and the resulting mixture is hydrogenated at room temperature and 60 psig. (4.3 kg./cm2) until the theoretical amount of hydrogen is consumed. After filtering to remove the catalyst, the solvent was evaporated to provide the desired 6a,10a-cis compound.