1-Butanol → HCID 20332638, Verbindung

HRID 1706886Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1706886
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:6]=1[Cl:12])=[O:4].[Br:13][C:14]1[CH:19]=[CH:18][C:17]([S:20][CH2:21][CH:22]([OH:25])[CH2:23]O)=[CH:16][CH:15]=1.CC1C=CC(S(O)(=O)=O)=CC=1.C(O)CCC>O.C1C=CC=CC=1>[Br:1][CH2:2][C:3]1([C:5]2[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:6]=2[Cl:12])[O:25][CH:22]([CH2:21][S:20][C:17]2[CH:18]=[CH:19][C:14]([Br:13])=[CH:15][CH:16]=2)[CH2:23][O:4]1

Komponenten

7

Edukt 4

HCID 2631-ButanolHCID 6101p-Toluenesulfonic acidHCID 758282-Bromo-1-(2,4-dichlorophenyl)ethan-1-oneHCID 203326623-[(4-Bromophenyl)sulfanyl]propane-1,2-diol

Produkt 1

HCID 20332638HCID 20332638, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 241BenzeneLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 13.6 parts of 2-bromo-1-(2,4-dichlorophenyl)-1-ethanone, 15.8 parts of 3-(4-bromophenylthio)-1,2-propanediol, 3 parts of 4-methylbenzenesulfonic acid, 180 parts of butanol and 90 parts of benzene is stirred and refluxed for 12 hours with water-separator. The reaction mixture is evaporated and the residue is dissolved in trichloromethane. The solution is stirred with silica gel for 30 minutes. The latter is filtered off and the filtrate is evaporated, yielding A+B 2-(bromomethyl)-4-(4-bromophenylthiomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane as a residue.

Aufarbeitung

  1. customThe reaction mixture is evaporated
  2. dissolutionthe residue is dissolved in trichloromethane
  3. stirringThe solution is stirred with silica gel for 30 minutes
  4. filtrationThe latter is filtered off
  5. customthe filtrate is evaporated

Quellen und Nachweise

ORD-Eintrag
ord-8b87f69815964b45bb4b3c3550555e66
Quelldatensatz
uspto-grants-1980_06
Patentnummer
US04209447

Notizen zur Reaktion

Wird geladen…