6-Phenyl-1,2,4-triazolo[4,3-a]pyrimidine → 6-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

HRID 1707047Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1707047
[C:1]1([C:7]2[CH:8]=[N:9][C:10]3[N:11]([CH:13]=[N:14][N:15]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)=O>[C:1]1([C:7]2[CH:8]=[N:9][C:10]3[N:15]([N:14]=[CH:13][N:11]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

3

Edukt 1

HCID 203333416-Phenyl-1,2,4-triazolo[4,3-a]pyrimidine

Produkt 1

HCID 100813826-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 284Formic AcidLösungsmittel

Versuchsvorschrift

A mixture of 1.0 g. of 6-(phenyl)-1,2,4-triazolo[4,3-a]pyrimidine and 10 ml. of 97% formic acid is refluxed for 5 hours and the excess formic acid is removed under reduced pressure. The solid residue is collected, washed with hexane and recrystallized from glacial acetic acid to give the product as crystals, m.p. 164°-167° C.

Aufarbeitung

  1. additionA mixture of 1.0 g
  2. customthe excess formic acid is removed under reduced pressure
  3. customThe solid residue is collected
  4. washwashed with hexane
  5. customrecrystallized from glacial acetic acid

Quellen und Nachweise

ORD-Eintrag
ord-b6f8ba44ce114f2c87513d73709ee6a4
Quelldatensatz
uspto-grants-1980_06
Patentnummer
US04209621

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