Acetic Acid → 6-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

HRID 1707048Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1707048
[C:1]1([C:7]([CH2:9]C=O)=N)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:12][C:13]1[N:17]=[CH:16][NH:15][N:14]=1.[C:18](O)(=O)C>>[C:1]1([C:7]2[CH:9]=[N:12][C:13]3[N:14]([N:15]=[CH:16][N:17]=3)[CH:18]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

4

Edukt 3

HCID 176Acetic AcidHCID 86737068(Phenyl)formimidoylacetaldehydeHCID 178418311HCID 178418311, Verbindung

Produkt 1

HCID 100813826-(Phenyl)-1,2,4-triazolo[1,5-a]pyrimidine

Versuchsvorschrift

An equimolar mixture of (phenyl)formimidoylacetaldehyde and 3-amino-1,2,4-triazole in glacial acetic acid (5 ml. acetic acid to 0.01 mole of reagents) is refluxed for 2 hours and allowed to cool to room temperature. The solid which separates is collected, washed with glacial acetic acid and dried. The solid is recrystallized from glacial acetic acid to give the product, m.p. 164°-167° C.

Aufarbeitung

  1. temperatureis refluxed for 2 hours
  2. customThe solid which separates is collected
  3. washwashed with glacial acetic acid
  4. customdried
  5. customThe solid is recrystallized from glacial acetic acid
  6. customto give the product, m.p. 164°-167° C.

Quellen und Nachweise

ORD-Eintrag
ord-283ad2879ae04803951bae3c9283c4f9
Quelldatensatz
uspto-grants-1980_06
Patentnummer
US04209621

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