2,2-Difluoro-2H-1,3-benzodioxole-4-sulfonyl chloride → HCID 67094937, Verbindung
Reaktionsgleichung
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[C:18]([NH2:20])[CH:17]=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[F:21][C:22]1([F:35])[O:26][C:25]2[CH:27]=[CH:28][CH:29]=[C:30]([S:31]([Cl:34])(=[O:33])=[O:32])[C:24]=2[O:23]1>>[ClH:34].[N:11]1([C:14]2[CH:19]=[C:18]([NH:20][S:31]([C:30]3[C:24]4[O:23][C:22]([F:35])([F:21])[O:26][C:25]=4[CH:27]=[CH:28][CH:29]=3)(=[O:32])=[O:33])[CH:17]=[CH:16][CH:15]=2)[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]1Komponenten
3
Versuchsvorschrift
The compound was prepared as described for Example 28 by reaction of 4-(5-aminophenyl)-piperazine-1-carboxylic acid tert-butyl ester with commercially available 2,2-Difluorobenzo[1,3]dioxole-4-sulfonyl chloride followed by deprotection under acidic conditions.
Aufarbeitung
- customThe compound was prepared
Quellen und Nachweise
- ORD-Eintrag