Methyl iodide → HCID 178503353, Verbindung
Reaktionsgleichung
[CH3:1][I:2].[Cl:3][C:4]1[CH:13]=[CH:12][C:11]([Cl:14])=[C:10]2[C:5]=1[CH:6]([CH3:16])[NH:7][C:8](=[S:15])[NH:9]2>CC(C)=O.C(OCC)C>[IH:2].[Cl:3][C:4]1[CH:13]=[CH:12][C:11]([Cl:14])=[C:10]2[C:5]=1[CH:6]([CH3:16])[NH:7][C:8]([S:15][CH3:1])=[N:9]2Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
Methyl iodide (0.73 ml, 11.7 mmol) was added to a suspension of 5,8-dichloro-4-methyl-3,4-dihydro-1H-quinazoline-2-thione (0.96 g, 3.9 mmol) in acetone (12 ml), and the mixture was stirred at room temperature overnight. The reaction was diluted with diethyl ether, and the precipitated product (1.31 g, 86%) was isolated by filtration as a white solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-dce822a163894ec5af59f7c95825da56
- Quelldatensatz
- uspto-grants-2010_09
- Patentnummer
- US07790732B2
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