2,3-Dimethyl-6-nitroquinoxaline → 6-Quinoxalinamine, 2,3-dimethyl-

HRID 1719495Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1719495
[CH3:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:13]([O-])=O)[CH:8]=2)[N:3]=1.[H][H]>[Pd]>[NH2:13][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([CH3:1])[C:11]([CH3:12])=[N:10]2

Komponenten

4

Edukt 2

HCID 6089992,3-Dimethyl-6-nitroquinoxalineHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 1460536-Quinoxalinamine, 2,3-dimethyl-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

A near solution of 2,3-dimethyl-6-nitroquinoxaline (62.9 g, 0.31 mole) in 1 L of absolute alcohol (Mallinkrodt) was hydrogenated in Parr apparatus using 5% Palladium on carbon 50% wet catalyst (Englehard). Hydrogen uptake (100% of theory) in 2 hours was noted. After the reduction stopped the catalyst was removed by filtration and the filtrate remaining concentrated to dryness in vacuo. The residue remaining was used without further purification as an intermediate in part C. Yield 52 g (96%).

Aufarbeitung

  1. customwas removed by filtration
  2. concentrationthe filtrate remaining concentrated to dryness in vacuo
  3. customThe residue remaining was used without further purification as an intermediate in part C

Quellen und Nachweise

ORD-Eintrag
ord-3760b66f7ddb4819b045f7fdcfb7243d
Quelldatensatz
uspto-grants-1985_09
Patentnummer
US04540693

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