Dimethyl Sulfoxide → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methyl phenyl)-6-(octahydro-2H-pyrazino[1,2-a]pyrazin-2-yl)-3-pyridinyl]-N,2-dimethylpropanamide
Reaktionsgleichung
[C:47](=[O:48])([O-:49])[O-:50].[CH2:1]1[CH:2]2[N:3]([CH2:4][CH2:5][NH:6]1)[CH2:7][CH2:8][NH:9][CH2:10]2.[CH3:53][S:54]([CH3:55])=[O:56].[F:11][C:12]([c:13]1[cH:14][c:15]([C:23]([C:24](=[O:25])[N:26]([CH3:27])[c:28]2[cH:29][n:30][c:31]([Cl:42])[cH:32][c:33]2-[c:34]2[c:35]([CH3:41])[cH:36][c:37]([F:40])[cH:38][cH:39]2)([CH3:43])[CH3:44])[cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]1)([F:45])[F:46].[K+:51].[K+:52]>>[CH2:1]1[CH:2]2[N:3]([CH2:4][CH2:5][N:6]1[c:31]1[n:30][cH:29][c:28]([N:26]([C:24]([C:23]([c:15]3[cH:14][c:13]([C:12]([F:11])([F:45])[F:46])[cH:18][c:17]([C:19]([F:20])([F:21])[F:22])[cH:16]3)([CH3:43])[CH3:44])=[O:25])[CH3:27])[c:33](-[c:34]3[c:35]([CH3:41])[cH:36][c:37]([F:40])[cH:38][cH:39]3)[cH:32]1)[CH2:7][CH2:8][NH:9][CH2:10]2
