Sodium Iodide → Ethyl 12-palmityloxy-stearate

HRID 1726429

Reaktionsgleichung

Reaktionsgleichung von HRID 1726429
C1(C)C=CC(S(O[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])(=O)=O)=CC=1.[OH:28][CH:29]([CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][C:40]([O:42][CH2:43][CH3:44])=[O:41].C(=O)([O-])[O-].[K+].[K+].[I-].[Na+]>C(#N)C>[CH2:26]([O:28][CH:29]([CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][C:40]([O:42][CH2:43][CH3:44])=[O:41])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH3:11]

Komponenten

6

Edukt 4

HCID 5238Sodium IodideHCID 11430Potassium CarbonateHCID 801711-Hexadecanol, 1-(4-methylbenzenesulfonate)HCID 345765112-Hydroxystearic acid ethyl ester

Produkt 1

HCID 86609679Ethyl 12-palmityloxy-stearate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Reaktionsbedingungen

Temperatur
81 °C

Versuchsvorschrift

Dissolve 10 mmol palmityl toluene-4-sulfonate, 10 mmol ethyl 12-hydroxystearate, 10 mmol anhydrous potassium carbonate and 0.5 mmol sodium iodide in 100 ml dry acetonitrile and heat to 81° C. with stirring for 6 hours. The reaction is cooled to room temperature. The solvent is evaporated and the products are suspended in MTBE and washed with 3×50 ml cold water. The solvent is evaporated to yield ethyl 12-palmityloxy-stearate.

Aufarbeitung

  1. temperatureThe reaction is cooled to room temperature
  2. customThe solvent is evaporated
  3. washwashed with 3×50 ml cold water
  4. customThe solvent is evaporated

Quellen und Nachweise

ORD-Eintrag
ord-a8b16bde96e64d13aeee4dd272f96f0e
Quelldatensatz
uspto-grants-2009_02
Patentnummer
US07491836B2

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