Hydroxylamine → HCID 19017744, Verbindung

Reaktionsgleichung

[CH3:1][C:2]1[O:6][N:5]=[CH:4][C:3]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8].[C:12]1(S(OCCC)(=O)=O)[CH:17]=CC=C[CH:13]=1.[NH2:25]O>>[CH3:1][C:2]1[O:6][N:5]=[C:4]([NH:25][CH2:13][CH2:12][CH3:17])[C:3]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8]

Komponenten

Edukt 3

HCID 787Hydroxylamine

HCID 220447Propyl benzenesulfonate

HCID 7009317Ethyl 5-methylisoxazole-4-carboxylate

Produkt 1

HCID 19017744HCID 19017744, Verbindung

Versuchsvorschrift

Ethyl 5-methylisoxazole-4-carboxylate is quaternized with propyl benzenesulfonate and the resulting quaternary salt is reacted with hydroxylamine to give the title compound according to the procedure of A. Alberola et al., Synthesis 203 (1988).

Quellen und Nachweise

ORD-Eintrag: ord-2d9b4c7d4fd34675adf80b48cf590927
Quelldatensatz: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05326776

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