Oxalyl chloride → 4-(Decyloxy)-3-(1,1-dimethylethyl)benzoyl chloride

HRID 1728894Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1728894
[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][C:13]=1[C:21]([CH3:24])([CH3:23])[CH3:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].C(Cl)(=O)C([Cl:28])=O>C(Cl)Cl.CN(C)C=O>[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([Cl:28])=[O:17])=[CH:14][C:13]=1[C:21]([CH3:24])([CH3:23])[CH3:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Komponenten

5

Edukt 2

HCID 65578Oxalyl chlorideHCID 19015379HCID 19015379, Verbindung

Produkt 1

HCID 190152784-(Decyloxy)-3-(1,1-dimethylethyl)benzoyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 6228DimethylformamideKatalysatorHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To 3.0 g of product from Example 131 in 30 ml of methylene chloride plus 2 drops of dimethylformamide is added 2.0 ml of oxalyl chloride via syringe. The reaction is stirred at room temperature for 18 hours, concentrated in vacuo, dissolved in diethyl ether and filtered through a pad of diatomaceous earth. The diethyl ether is concentrated in vacuo to give 3.15 g of the desired product as a yellow oil.

Aufarbeitung

  1. concentrationconcentrated in vacuo
  2. dissolutiondissolved in diethyl ether
  3. filtrationfiltered through a pad of diatomaceous earth
  4. concentrationThe diethyl ether is concentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-524508adfbcf48e293fe47c8c6cef590
Quelldatensatz
uspto-grants-1994_07
Patentnummer
US05328921

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