HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Chloro-amitriptyline → Amitriptyline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Chloro-amitriptyline | HCID 103696 | — |
| Edukt | D-Tartaric acid | HCID 439655 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | Amitriptyline | HCID 2160 | — |
Reaktionsschritte
1-Chloro-amitriptyline (196 mg) in 3 ml. absolute ethanol was added to an ethanolic solution of 1.1 eq. d-tartaric acid and warmed for 5-10 mins. The title compound was precipitated with ethyl ether as a white powder. After purity and identification checks, the overall yield from amitriptyline base was 32%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US03991103 |
| Quelldatensatz | uspto-grants-1976_11 |
| ORD ID | ord-b196b6985ee74a0ebcf6527350330854 |
| Quellennotiz | uspto-grants-1976_11 |