Oxalyl chloride → 2-Trifluoromethylhexanoyl chloride

HRID 1732516Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1732516
[F:1][C:2]([F:12])([F:11])[CH:3]([CH2:7][CH2:8][CH2:9][CH3:10])[C:4](O)=[O:5].C(Cl)(=O)C([Cl:16])=O>>[F:1][C:2]([F:12])([F:11])[CH:3]([CH2:7][CH2:8][CH2:9][CH3:10])[C:4]([Cl:16])=[O:5]

Komponenten

3

Edukt 2

HCID 65578Oxalyl chlorideHCID 157451932-Trifluoromethylhexanoic acid

Produkt 1

HCID 202859472-Trifluoromethylhexanoyl chlorideAusbeute 90 %

Versuchsvorschrift

2-Trifluoromethylhexanoic acid (2.3 g.) was added dropwise to 10 g. oxalyl chloride (10 g.) and the mixture heated to reflux for 2 hours. Distillation of the reaction mixture after this time yielded 2-trifluoromethylhexanoyl chloride (2.27 g.; 90%), b.p. 67°-70°/43 mmHg.

Aufarbeitung

  1. temperatureto reflux for 2 hours
  2. distillationDistillation of the reaction mixture after this time

Quellen und Nachweise

ORD-Eintrag
ord-603a6411cb8841c5811ecfa8dd9d47e3
Quelldatensatz
uspto-grants-1980_12
Patentnummer
US04237276

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