2-Propenal, 3-[4-(1,1-dimethylethyl)phenyl]-2-methyl- → 3-(4-tert-Butylphenyl)-2-methylprop-2-en-1-ol

HRID 1733273

Reaktionsgleichung

Reaktionsgleichung von HRID 1733273
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[C:12]([CH3:15])[CH:13]=[O:14])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[BH4-].[Na+]>CO>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([CH:11]=[C:12]([CH3:15])[CH2:13][OH:14])=[CH:9][CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Komponenten

4

Edukt 2

HCID 1146592-Propenal, 3-[4-(1,1-dimethylethyl)phenyl]-2-methyl-HCID 4311764Sodium borohydride

Produkt 1

HCID 543813673-(4-tert-Butylphenyl)-2-methylprop-2-en-1-ol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

404.5 g of 3-(p-tert.butyl-phenyl)-2-methyl-acrolein are dissolved in 2500 ml of methanol and treated portionwise with 38 g of sodium borohydride while cooling with ice. Subsequently, the mixture is stirred at room temperature for 2.5 hours, poured into 2500 ml of ice-cold 2-N hydrochloric acid and exhaustively extracted with hexane. The combined hexane extracts are washed neutral with water, dried over sodium sulphate and evaporated. Vacuum distillation yields pure 3-(p-tert.butyl-phenyl)-2-methyl-allyl alcohol of boiling point 119° C./0.005 Torr.

Aufarbeitung

  1. temperaturewhile cooling with ice
  2. extractionexhaustively extracted with hexane
  3. washThe combined hexane extracts are washed neutral with water
  4. dry with materialdried over sodium sulphate
  5. customevaporated
  6. distillationVacuum distillation

Quellen und Nachweise

ORD-Eintrag
ord-c9b3e26ab02241aaa76378731f7f9858
Quelldatensatz
uspto-grants-1980_12
Patentnummer
US04241058

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