Triphosgene → HCID 19076265, Verbindung

HRID 1735943Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1735943
[NH2:1][N:2]1[CH:10]=[C:8]([CH3:9])[C:6](=[O:7])[NH:5][C:3]1=[O:4].[Cl:11][C:12](Cl)([O:14]C(=O)OC(Cl)(Cl)Cl)Cl>O1CCCC1>[Cl:11][C:12]([NH:1][N:2]1[CH:10]=[C:8]([CH3:9])[C:6](=[O:7])[NH:5][C:3]1=[O:4])=[O:14]

Komponenten

4

Edukt 2

HCID 94429TriphosgeneHCID 118191591-Amino thymine

Produkt 1

HCID 19076265HCID 19076265, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

1-Amino thymine (7, 12.5 g, 0.1 mol) is dissolved in tetrahydrofuran (500 mL) and the solution is cooled to 0° C. and a 2M solution of triphosgene in THF (150 mL) is added and the reaction is stirred for 4 hours. The solution is evaporated to a solid, which is used as is in the next reaction.

Aufarbeitung

  1. customThe solution is evaporated to a solid, which
  2. customas is in the next reaction

Quellen und Nachweise

ORD-Eintrag
ord-83ba5ceef3a84098b64a3d73fb7698e3
Quelldatensatz
uspto-grants-1996_07
Patentnummer
US05539082

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