HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Formaldehyde → 9-(4'-(2"-Hydroxy1"-oxoethyl)-benzylidene)-8-ketotricyclo[5.2.1.02.6]decane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Formaldehyde | HCID 712 | — |
| Edukt | 4,7-Methano-5H-inden-5-one, octahydro- | HCID 96509 | — |
| Edukt | 3-Ethyl-1,3-benzothiazol-3-ium bromide | HCID 182081 | — |
| Edukt | Sodium Methoxide | HCID 10942334 | — |
| Edukt | 9-(4-Formylbenzylidene)-8-ketotricyclo[5.2.1.02,6]decane | HCID 54022151 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | 9-(4'-(2"-Hydroxy1"-oxoethyl)-benzylidene)-8-ketotricyclo[5.2.1.02.6]decane | HCID 56973744 | — |
Reaktionsschritte
0.8 g (3.5 mmol) of 3-ethylbenzothiazolium bromide and triethylamine are added to a mixture of 35 mmol of 9-(4'-formylbenzylidene)-8-ketotricyclo-[5.2.1.02.6 ] decane (prepared from 8-ketotricyclo-[5. 2.1.02.6 ] decane and terephthaldehyde di ethyl acetal (sic) in the presence of sodium methylate and subsequent acetal cleavage) and 1.2 g of paraformaldehyde in 70 ml of ethanol, and the mixture is heated under reflux. After working up analogously to Example 1, 9-(4'-(2"-hydroxy-1"-oxoethyl)-benzylidene)-8-ketotricyclo[5.2.1. 02.6 ]-decane is obtained. The spectra correspond to the expected compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05968482 |
| Quelldatensatz | uspto-grants-1999_10 |
| ORD ID | ord-8fde504737a24002841bfb6229903395 |
| Quellennotiz | uspto-grants-1999_10 |