反应详情

0.8 g (3.5 mmol) of 3-ethylbenzothiazolium bromide and triethylamine are added to a mixture of 35 mmol of 9-(4'-formylbenzylidene)-8-ketotricyclo-[5.2.1.02.6 ] decane (prepared from 8-ketotricyclo-[5. 2.1.02.6 ] decane and terephthaldehyde di ethyl acetal (sic) in the presence of sodium methylate and subsequent acetal cleavage) and 1.2 g of paraformaldehyde in 70 ml of ethanol, and the mixture is heated under reflux. After working up analogously to Example 1, 9-(4'-(2"-hydroxy-1"-oxoethyl)-benzylidene)-8-ketotricyclo[5.2.1. 02.6 ]-decane is obtained. The spectra correspond to the expected compound.

1. temperaturethe mixture is heated
2. temperatureunder reflux