Methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate → Methyl 3-carboxymethoxy-5-hydroxybenzoate

HRID 1740316Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1740316
C([O:8][C:9]([CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:20]=[C:21]([OH:23])[CH:22]=1)[C:16]([O:18][CH3:19])=[O:17])=[O:10])C1C=CC=CC=1>[Pd].CO>[C:9]([CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:20]=[C:21]([OH:23])[CH:22]=1)[C:16]([O:18][CH3:19])=[O:17])([OH:10])=[O:8]

Komponenten

4

Edukt 1

HCID 21838035Methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate

Produkt 1

HCID 11253108Methyl 3-carboxymethoxy-5-hydroxybenzoateAusbeute 103,5 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

10% palladium on carbon (0.1 g) was added to a mixture of methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate (1 g) in methanol (20 ml) and the mixture was subjected to catalytic reduction at ambient temperature under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated in vacuo to give methyl 3-carboxymethoxy-5-hydroxybenzoate (0.74 g).

Aufarbeitung

  1. customwas subjected to catalytic reduction at ambient temperature under atmospheric pressure
  2. customThe catalyst was removed by filtration
  3. customthe filtrate was evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-ab7f2c9943814927bc5b195fdfcfcd25
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05968985

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