Hydrochloric Acid → 5,6,7,8-Tetrahydro-3-methoxy5,5,8,8-tetramethyl-2-naphthaldoxime

HRID 1742389

Reaktionsgleichung

Reaktionsgleichung von HRID 1742389
[CH3:1][O:2][C:3]1[C:4]([CH:17]=O)=[CH:5][C:6]2[C:7]([CH3:16])([CH3:15])[CH2:8][CH2:9][C:10]([CH3:14])([CH3:13])[C:11]=2[CH:12]=1.[Cl-].[OH:20][NH3+:21].Cl>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[C:4]([CH:17]=[N:21][OH:20])=[CH:5][C:6]2[C:7]([CH3:16])([CH3:15])[CH2:8][CH2:9][C:10]([CH3:14])([CH3:13])[C:11]=2[CH:12]=1

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 21645Hydroxylamine HClHCID 147265222-Formyl-5,6,7,8-tetrahydro-3-methoxy-5,5,8,8tetramethylnaphthalene

Produkt 1

HCID 867451925,6,7,8-Tetrahydro-3-methoxy5,5,8,8-tetramethyl-2-naphthaldoxime

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

5 g (20 millimoles) of (5,6,7,8-tetrahydro-3-methoxy5,5,8,8-tetramethyl-2-naphthaldehyde and 2.1 g (30 millimoles) of hydroxylammonium chloride in 32.5 ml of dry pyridine were refluxed for 2 hours. The mixture was then allowed to cool, poured onto water and acidified with concentrated hydrochloric acid, and the precipitate which had separated out was filtered off under suction and dried to give 5.1 g of (5,6,7,8-tetrahydro-3-methoxy5,5,8,8-tetramethyl-2-naphthaldoxime of melting point 182°-183° C.

Aufarbeitung

  1. temperatureto cool
  2. additionpoured onto water
  3. customthe precipitate which had separated out
  4. filtrationwas filtered off under suction
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-21a1c780869845ccbbeb35b0c4f8c088
Quelldatensatz
uspto-grants-1994_08
Patentnummer
US05338749

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