HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Amino-5-(4-morpholinopiperidin-1-yl)benzonitrile → N-[2-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Amino-5-(4-morpholinopiperidin-1-yl)benzonitrile | HCID 22227997 | — |
| Edukt | 5-Methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxylic chloride | HCID 22228086 | — |
| Produkt | N-[2-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxamide | HCID 22228003 | 39,9% |
Reaktionsschritte
By the reaction and treatment in the same manner as in Example 150 using 5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxylic chloride (0.9 g) and 2-amino-5-(4-morpholinopiperidin-1-yl)benzonitrile (0.9 g), the title compound (0.67 g) was obtained, melting point: 210–212° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07015218B1 |
| Quelldatensatz | uspto-grants-2006_03 |
| ORD ID | ord-3d247a9990724c99899a54fd267f7176 |
| Quellennotiz | uspto-grants-2006_03 |