HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride → 1-(4-Chlorophenyl)-5-methyl-N-[4-(4-morpholinopiperidin-1-yl)-3-trifluoromethylphenyl]pyrazole-4-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride | HCID 2776128 | — |
| Edukt | 4-(4-Morpholinopiperidin-1-yl)-3-trifluoromethylaniline | HCID 22227917 | — |
| Produkt | 1-(4-Chlorophenyl)-5-methyl-N-[4-(4-morpholinopiperidin-1-yl)-3-trifluoromethylphenyl]pyrazole-4-carboxamide | HCID 22227989 | 66,5% |
Reaktionsschritte
By the reaction and treatment in the same manner as in Example 150 using 1-(4-chlorophenyl)-5-methylpyrazole-4-carboxylic chloride (0.77 g) and 4-(4-morpholinopiperidin-1-yl)-3-trifluoromethylaniline (1 g), the title compound (1.1 g) was obtained, melting point: 193–194° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07015218B1 |
| Quelldatensatz | uspto-grants-2006_03 |
| ORD ID | ord-9381bcd321934b4984ef3faecdfb6714 |
| Quellennotiz | uspto-grants-2006_03 |