Hydrogen iodide → 4-Iodo-6-(quinolin-4-yl)pyrimidine

HRID 1752007Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1752007
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](B(O)O)=[CH:3][CH:2]=1.Cl[C:15]1[CH:20]=[C:19](Cl)[N:18]=[CH:17][N:16]=1.[IH:22]>>[I:22][C:15]1[CH:20]=[C:19]([C:4]2[C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[N:1]=[CH:2][CH:3]=2)[N:18]=[CH:17][N:16]=1

Komponenten

4

Edukt 3

HCID 24841Hydrogen iodideHCID 709434,6-DichloropyrimidineHCID 2762748Quinoline-4-boronic acid

Produkt 1

HCID 513558444-Iodo-6-(quinolin-4-yl)pyrimidine

Versuchsvorschrift

The compound was prepared according to Example 1 using quinoline-4-boronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.

Aufarbeitung

  1. customThe compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-fd50751226b44104a2b5e276d2e7c47a
Quelldatensatz
uspto-grants-2015_10
Patentnummer
US09162987B2

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