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Dimethylformamide → HCID 117666823, Verbindung

HRID 1753677
Notizen
Druckvorschau

Reaktionsgleichung

Reaktionsgleichung von HRID 1753677
[C:1]1([S:7][C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21].C(=O)([O-])[O-].[K+].[K+].CN(C=O)C>C1(C)C=CC=CC=1.O>[C:1]1([S:7][C:8]2[CH:13]=[CH:12][C:11]([O:14][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])=[CH:10][CH:9]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1
KomponentenVersuchsvorschriftAufarbeitungQuellen und NachweiseNotizen zur Reaktion

Komponenten

7

Edukt 4

HCID 6228DimethylformamideHCID 81011-BromohexaneHCID 11430Potassium CarbonateHCID 113101954-(phenylthio)phenol

Produkt 1

HCID 117666823HCID 117666823, VerbindungAusbeute 90 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962
Water
Lösungsmittel
HCID 1140TolueneLösungsmittel

Versuchsvorschrift

A solution was prepared by combining 15 g of (4-hydroxyphenyl) phenyl sulfide which had been synthesized according to the well-known formulation, 11 g of 1-bromohexane, 9 g of potassium carbonate, and 30 g of DMF. The solution was aged at 80° C. for 16 hours. The aged solution was cooled to room temperature, to which 30 g of water was added to quench the reaction. To the solution, 50 g of toluene was added for extraction. The organic layer was separated and washed with sodium hydroxide aqueous solution and water in sequence. On subsequent concentration in vacuum, 16 g of the target compound, (4-hexyloxyphenyl) phenyl sulfide was obtained as oily matter. Yield 90%.

Aufarbeitung

  1. customA solution was prepared
  2. customhad been synthesized
  3. additionwas added
  4. customto quench
  5. customthe reaction
  6. customThe organic layer was separated
  7. washwashed with sodium hydroxide aqueous solution and water in sequence
  8. concentrationOn subsequent concentration in vacuum, 16 g of the target compound

Quellen und Nachweise

ORD-Eintrag
ord-88a342cc91cc40d68d522657fb1c9b58
Quelldatensatz
uspto-grants-2015_10
DOI
10.6084/m9.figshare.5104873.v1
Patentnummer
US09164384B2

Notizen zur Reaktion

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