Chlorine → 1-Chloro-2-(difluoromethoxy)benzene

HRID 1756278

Reaktionsgleichung

Reaktionsgleichung von HRID 1756278
[F:1][CH:2]([F:10])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[Cl:11]Cl>FC(F)(F)C1C=CC=C(C(F)(F)F)C=1.[Cl-].[K+]>[Cl:11][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[O:3][CH:2]([F:10])[F:1]

Komponenten

5

Edukt 2

HCID 24526Chlorine2×HCID 68015(Difluoromethoxy)benzene2×

Produkt 1

HCID 134050971-Chloro-2-(difluoromethoxy)benzene

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 4873Potassium ChlorideKatalysatorHCID 223106Benzene, 1,3-bis(trifluoromethyl)-Lösungsmittel

Versuchsvorschrift

0.5 g of potassium chloride and 10 g of difluoromethoxybenzene were placed in 100 ml of 1,3-bistrifluoromethylbenzene and chlorine was then introduced at 100° C. under UV irradiation. A further 20 g of difluoromethoxybenzene were metered in over a period of 1 hour. When the chlorine uptake had ended, the mixture was purged with nitrogen and then distilled to give 35.5 g of chlorodifluoromethoxybenzene (boiling point: 144° C., refractive index nD20 : 1.4479).

Aufarbeitung

  1. customwere metered in over a period of 1 hour
  2. customthe mixture was purged with nitrogen
  3. distillationdistilled

Quellen und Nachweise

ORD-Eintrag
ord-7bcc8a3fe4fc4ac4b265c38b8f15a686
Quelldatensatz
uspto-grants-1995_08
Patentnummer
US05440051

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