HCID 13102700, Verbindung → 3-Pyridinamine, 6-(3,4-dichlorophenoxy)-

HRID 1758002Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1758002
[Cl:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][C:17]=1[Cl:18])[O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][N:7]=1>C(O)C.[Pd]>[Cl:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][C:17]=1[Cl:18])[O:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][N:7]=1

Komponenten

4

Edukt 1

HCID 13102700HCID 13102700, Verbindung

Produkt 1

HCID 5148873-Pyridinamine, 6-(3,4-dichlorophenoxy)-

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

The 2-(3,4-dichlorophenoxy)-5-nitropyridine described above was divided into 4 portions of 23.7 g each, and each portion was then hydrogenated in absolute ethanol employing a palladium catalyst as well known in the art. After removal of the catalyst, the ethanol filtrates were combined and evaporated to dryness. The residue which remained was diluted with isopropyl alcohol and hexane and then chilled. The resulting solid was collected by filtration and vacuum dried to give 70.8 g of 2-(3,4-dichlorophenoxy)-5-pyridinamine as a rose colored powder, m.p. 78°-79.3° C.

Aufarbeitung

  1. customAfter removal of the catalyst
  2. customevaporated to dryness
  3. additionThe residue which remained was diluted with isopropyl alcohol and hexane
  4. temperaturechilled
  5. filtrationThe resulting solid was collected by filtration and vacuum
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-c413b7171c6c49f4bc18813bf7d962e8
Quelldatensatz
uspto-grants-1983_02
Patentnummer
US04371537

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