Triethylamine → HCID 20509898, Verbindung

HRID 1758233Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1758233
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N+:10]([O-:12])=[O:11])=[C:6]([CH:9]=1)[CH2:7]Cl.[CH3:13][O:14][CH:15]([O:18][CH3:19])[CH2:16][NH2:17].C(N(CC)CC)C>C(O)C>[CH3:13][O:14][CH:15]([O:18][CH3:19])[CH2:16][NH:17][CH2:7][C:6]1[CH:9]=[C:2]([CH3:1])[CH:3]=[CH:4][C:5]=1[N+:10]([O-:12])=[O:11]

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 89728Aminoacetaldehyde dimethyl acetalHCID 2724031alpha-Chloro-5-methyl-2-nitrotoluene

Produkt 1

HCID 20509898HCID 20509898, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel2×

Versuchsvorschrift

A solution of 43 g of 5-methyl-2-nitrobenzyl chloride in 200 ml of ethanol is added drop-wise to a solution of 40 g of aminoacetaldehyde dimethylacetal and 40 g of triethylamine in 300 ml of ethanol at reflux temperature, and the solution is heated for 18 hours at reflux. It is then evaporated in a vacuum until dry and the residue is dissolved in ethyl acetate, and extracted several times with water. After the organic phase is dried and evaporated, the heading compound remains as a reddish oil.

Aufarbeitung

  1. temperatureat reflux temperature
  2. temperaturethe solution is heated for 18 hours
  3. temperatureat reflux
  4. customIt is then evaporated in a vacuum
  5. customuntil dry
  6. dissolutionthe residue is dissolved in ethyl acetate
  7. extractionextracted several times with water
  8. customAfter the organic phase is dried
  9. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-b50896deb4e84efe88ee8caf32814066
Quelldatensatz
uspto-grants-1983_02
Patentnummer
US04372956

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