HCID 20509898, Verbindung → HCID 20509920, Verbindung

HRID 1758234Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1758234
[CH3:1][O:2][CH:3]([O:17][CH3:18])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([CH3:13])[CH:10]=[CH:9][C:8]=1[N+:14]([O-])=O>C(O)C.[Pd]>[CH3:1][O:2][CH:3]([O:17][CH3:18])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([CH3:13])[CH:10]=[CH:9][C:8]=1[NH2:14]

Komponenten

4

Edukt 1

HCID 20509898HCID 20509898, Verbindung

Produkt 1

HCID 20509920HCID 20509920, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

The crude aminoacetal obtained in step (c) is dissolved in 700 ml of ethanol and is hydrogenated at room temperature and at atmospheric pressure, in the presence of 3 g of palladium catalyst (10% Pd on carbon). After the catalyst is filtered off and the filtrate evaporated, the heading compound remains as an orange oil, which is converted into the hydrochloride using methanolic hydrochloric acid.

Aufarbeitung

  1. filtrationAfter the catalyst is filtered off
  2. customthe filtrate evaporated

Quellen und Nachweise

ORD-Eintrag
ord-8186f80460ea49798f8a047ceef94a27
Quelldatensatz
uspto-grants-1983_02
Patentnummer
US04372956

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