Potassium Carbonate → HCID 13023013, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[OH:14])=[CH:6][CH:7]=1.[CH2:15]([CH:17]1[O:19][CH2:18]1)Br.C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[Cl:1][C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[O:14][CH2:15][CH:17]2[O:19][CH2:18]2)=[CH:6][CH:7]=1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 3-chloro-6-(2-hydroxyphenyl)pyridazine (2.69 g.), epibromohydrin (4.5 ml.), anhydrous potassium carbonate (3.6 g.) and dry butane-2-one (100 ml.) was stirred and heated under reflux for 16 hours. The mixture was filtered and the filtrate was evaporated to dryness and the residue was twice recrystallized from ethanol to give 3-chloro-6-(2-epoxypropoxyphenyl)pyridazine, m.p. 118°-119°.