Sodium Hydroxide → HCID 20307400, Verbindung

HRID 1763784

Reaktionsgleichung

Reaktionsgleichung von HRID 1763784
Br[CH2:2][CH:3]=[O:4].[CH3:5][CH:6]([NH2:12])[CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10].[OH-].[Na+]>O>[CH3:5][CH:6]([NH:12][CH2:2][CH:3]=[O:4])[CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10]

Komponenten

5

Edukt 3

HCID 14798Sodium HydroxideHCID 342045-Methyl-2-hexylamineHCID 105131Acetaldehyde, bromo-

Produkt 1

HCID 20307400HCID 20307400, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

The diethylacetal of 2-bromoacetaldehyde (40 grams) and 1,4-dimethylpentylamine (50 grams) were charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture was heated at a temperature of about 100° C. for a period of about 3 hours. After this time sodium hydroxide (10 grams) dissolved in water (100 ml) was added and the resulting mixture stirred for about 30 minutes. The reaction mixture was then extracted with ether. The ether extract was separated, dried over magnesium sulfate, filtered and stripped of solvent under reduced pressure to yield the desired product the diethylacetal of 2-(1,4-dimethylpentylamino)acetaldehyde having a boiling point of 95° C. at 1 mm of Hg pressure.

Aufarbeitung

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. additionwas added
  4. extractionThe reaction mixture was then extracted with ether
  5. extractionThe ether extract
  6. customwas separated
  7. dry with materialdried over magnesium sulfate
  8. filtrationfiltered

Quellen und Nachweise

ORD-Eintrag
ord-dd0ee538c13e454d8bc039c1439d89ca
Quelldatensatz
uspto-grants-1978_09
Patentnummer
US04113464

Verknüpfte Notizen

Wird geladen…