Quinoline → 3-Buten-2-ol, 1,1-dimethoxy-2-methyl-

HRID 1764561Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1764561
[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[C:5]#[CH:6].N1C2C(=CC=CC=2)C=CC=1.[H][H]>[Pd]>[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[CH:5]=[CH2:6]

Komponenten

5

Edukt 3

HCID 7047QuinolineHCID 128752274,4-Dimethoxy-3-methyl-but-1-yn-3-olHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 110080503-Buten-2-ol, 1,1-dimethoxy-2-methyl-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

198 G. of 4,4-dimethoxy-3-methyl-but-1-yn-3-ol are dissolved in 960 ml. of high-boiling petroleum ether and, after the addition of 19.35% palladium catalyst and 19.3 g. of quinoline, hydrogenated under normal conditions. After the uptake of 33.5 l. of hydrogen, the hydrogenation is stopped. The catalyst is filtered off. The filtrate is evaporated under reduced pressure. The remaining 4,4-dimethoxy-3-methyl-but-1-en-3-ol boils, after rectification, at 70°-72° C./18 mm Hg.

Aufarbeitung

  1. filtrationThe catalyst is filtered off
  2. customThe filtrate is evaporated under reduced pressure
  3. customat 70°-72° C.

Quellen und Nachweise

ORD-Eintrag
ord-e76f93dd4ca34e539ed05c2321c99da9
Quelldatensatz
uspto-grants-1978_09
Patentnummer
US04116975

Notizen zur Reaktion

Wird geladen…