4-Nitrophenol → 4-Nitrophenoxyacetonitrile

HRID 1770848Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1770848
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].Br[CH2:12][C:13]#[N:14].C([O-])([O-])=O.[K+].[K+]>CC(C)=O.O>[C:13]([CH2:12][O:10][C:7]1[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=1)#[N:14]

Komponenten

6

Edukt 3

HCID 9804-NitrophenolHCID 11430Potassium CarbonateHCID 11534Bromoacetonitrile

Produkt 1

HCID 1418544-Nitrophenoxyacetonitrile

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittel2×HCID 962WaterLösungsmittel

Versuchsvorschrift

4-Nitrophenol (10 g), bromoacetonitrile (6 mL) and K2CO3 (15 g) were suspended in acetone (100 mL). The yellow solution was stirred at rt overnight. The reaction mixture was diluted with water (100 mL) and acetone was removed under reduced pressure. The light-yellow precipitate was collected by filtration, washed with water and dried to give O-cyanomethyl-4-nitrophenol.

Aufarbeitung

  1. customwas removed under reduced pressure
  2. filtrationThe light-yellow precipitate was collected by filtration
  3. washwashed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-1f231dc690f044099d2edc7e17bb208e
Quelldatensatz
uspto-grants-2016_02
Patentnummer
US09248190B2

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