Hydrogen Bromide → 2-Carboxyethyl 5-amino-4-oxopentanoate hydrobromide

Reaktionsgleichung

C([NH:8][CH2:9][C:10](=[O:25])[CH2:11][CH2:12][C:13]([O:15][CH2:16][CH2:17][C:18]([O:20]C(C)(C)C)=[O:19])=[O:14])(OC(C)(C)C)=O.[BrH:26]>C(O)(=O)C>[BrH:26].[NH2:8][CH2:9][C:10](=[O:25])[CH2:11][CH2:12][C:13]([O:15][CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[O:14]

Komponenten

Versuchsvorschrift

This compound was prepared from the product of 4a (5.43 g; 15.1 mmol) and 30% HBr in acetic acid (15 mL) according to Example 1c. 3.38 g (79%) product was obtained (amber gum that did not solidify).

Quellen und Nachweise

ORD-Eintrag: ord-aadb54df4689413ba507b93820dbae30
Quelldatensatz: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09249086B2

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Komponenten

Edukt 2

HCID 260Hydrogen Bromide

HCID 900345122-(t-butoxycarbonyl)ethyl 5-(Boc-amino)-4-oxopentanoate

Produkt 1

HCID 900344812-Carboxyethyl 5-amino-4-oxopentanoate hydrobromideAusbeute 79 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

This compound was prepared from the product of 4a (5.43 g; 15.1 mmol) and 30% HBr in acetic acid (15 mL) according to Example 1c. 3.38 g (79%) product was obtained (amber gum that did not solidify).

Quellen und Nachweise

ORD-Eintrag: ord-aadb54df4689413ba507b93820dbae30
Quelldatensatz: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09249086B2

Notizen zur Reaktion

Wird geladen…