Carbon Dioxide → 2-(prop-2-yn-1-yl)pent-4-ynoic acid

Reaktionsgleichung

[CH2:1]([C:4]([CH2:11][C:12]#[CH:13])(C(O)=O)[C:5]([OH:7])=[O:6])[C:2]#[CH:3].C(=O)=O>>[CH2:1]([CH:4]([CH2:11][C:12]#[CH:13])[C:5]([OH:7])=[O:6])[C:2]#[CH:3]

Komponenten

Edukt 2

HCID 280Carbon Dioxide

HCID 12686700HCID 12686700, Verbindung

Produkt 1

HCID 136736532-(prop-2-yn-1-yl)pent-4-ynoic acidAusbeute 79,9 %

Versuchsvorschrift

The dipropargylmalonic acid (26 gm, 0.443 mol) was heated neat at 135 C until CO2 stopped evolving. It was then allowed to cool to an oil. The oil was distilled at 0.5 psi. The remaining oily residue in the distillation flask and solid were combined (15.7 gm, 79.9% yield) and was used as is in the next step.

Aufarbeitung

temperatureto cool to an oil
distillationThe oil was distilled at 0.5 psi

Quellen und Nachweise

ORD-Eintrag: ord-06bb52966caa440bb7db883f19e241cb
Quelldatensatz: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09265838B2

Notizen zur Reaktion

Wird geladen…