Acetic Anhydride → HCID 11041076, Verbindung

HRID 1779707Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1779707
[CH3:1][CH:2]([C:7](=[O:13])[CH2:8][CH2:9][C:10]([CH3:12])=[CH2:11])[CH2:3][C:4]([OH:6])=O.C(OC(=O)C)(=O)C>>[CH3:1][C:2]1[CH:7]([CH2:8][CH:9]=[C:10]([CH3:11])[CH3:12])[O:13][C:4](=[O:6])[CH:3]=1

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 110195357-Octenoic acid, 3,7-dimethyl-4-oxo-

Produkt 1

HCID 11041076HCID 11041076, Verbindung

Versuchsvorschrift

The thus-obtained 3,7-dimethyl-4-oxo-7-octenoic acid is then dissolved in a solvent and an equivalent amount or a somewhat excessive amount of acetic anhydride is added thereto and heated under reflux in the presence of an acid catalyst, whereby the acid is cyclized and dehydrated along with isomerization of the terminal double bond to give 3,7-dimethyl-2,6-octadien-4-olide. As the solvent in this process, usable is a hydrocarbon solvent such as pentane, hexane, heptane, benzene, toluene, xylene or the like. Especially preferred is toluene. As the acid catalyst, usable is an organic acid such as acetic acid, para-toluene-sulfonic acid, camphor-sulfonic acid or the like.

Aufarbeitung

  1. temperatureheated
  2. temperatureunder reflux in the presence of an acid catalyst, whereby the acid

Quellen und Nachweise

ORD-Eintrag
ord-252282c9a713493783db2779cb37c19f
Quelldatensatz
uspto-grants-1997_05
Patentnummer
US05627288

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