Hydrochloric Acid → 2-[4-(Aminomethyl)phenyl]ethan-1-ol

HRID 1781392Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1781392
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([CH2:7][CH2:8][OH:9])=[CH:5][CH:4]=1)#[N:2].Cl>C(O)C.[Pd]>[OH:9][CH2:8][CH2:7][C:6]1[CH:10]=[CH:11][C:3]([CH2:1][NH2:2])=[CH:4][CH:5]=1

Komponenten

5

Edukt 2

HCID 313Hydrochloric AcidHCID 28008154-(2-Hydroxyethyl)benzonitrile

Produkt 1

HCID 226014582-[4-(Aminomethyl)phenyl]ethan-1-ol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 0.74 g (0.005 mol) of p-cyanophenethyl alcohol in 50 ml of ethanol containing 10 ml of concentrated hydrochloric acid was hydrogenated at 30 psi using 0.1 g 5% Pd/C for 72 hours. The catalyst was removed by filtration and the solvent was removed under reduced pressure.

Aufarbeitung

  1. customfor 72 hours
  2. customThe catalyst was removed by filtration
  3. customthe solvent was removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-318a0d649152403aa70213f1e775d186
Quelldatensatz
uspto-grants-1997_05
Patentnummer
US05633247

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