Triethylamine → N1-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(2-furylmethyl)amino]-2-hydroxypropyl)-5-methyl-N3,N3-dipropylisophthalamide

Reaktionsgleichung

[C:1]([OH:4])(=O)[CH3:2].[NH2:5][CH2:6][C@@H:7]([OH:37])[C@@H:8]([NH:18][C:19](=[O:36])[C:20]1[CH:34]=[C:33]([CH3:35])[CH:32]=[C:22]([C:23]([N:25]([CH2:29][CH2:30][CH3:31])[CH2:26][CH2:27][CH3:28])=[O:24])[CH:21]=1)[CH2:9][C:10]1[CH:15]=[C:14]([F:16])[CH:13]=[C:12]([F:17])[CH:11]=1.O1C=[CH:41][C:40](C=O)=[CH:39]1.C(N(CC)CC)C>C(O)C.[Pd]>[F:16][C:14]1[CH:15]=[C:10]([CH:11]=[C:12]([F:17])[CH:13]=1)[CH2:9][C@H:8]([NH:18][C:19](=[O:36])[C:20]1[CH:34]=[C:33]([CH3:35])[CH:32]=[C:22]([C:23]([N:25]([CH2:26][CH2:27][CH3:28])[CH2:29][CH2:30][CH3:31])=[O:24])[CH:21]=1)[C@H:7]([OH:37])[CH2:6][NH:5][CH2:41][C:40]1[O:4][CH:1]=[CH:2][CH:39]=1