Methane → HCID 178518411, Verbindung
Reaktionsgleichung
C1(N[C:8]2[C:9]3[S:28][CH2:27][CH2:26][C:10]=3N=C(N3CCN(C4C=CC=CC=4)CC3)N=2)CCCCC1.[NH2:29][C:30]([NH2:32])=[O:31].C.[OH-:34].[Na+]>>[N:29]1[C:10]2[CH:26]=[CH:27][S:28][C:9]=2[C:8]([OH:34])=[N:32][C:30]=1[OH:31]Komponenten
5
Versuchsvorschrift
10.0 g (64.0 mmol) of methylester 3-aminothiophene-2-carboxylate (I) and 19.0 g (31.60 mmol) of urea are mixed and melted for 2 hours at 200° C. After cooling, the reaction mixture is dissolved in 1 molar sodium hydroxide solution and decolorized with activated charcoal. It is filtered and the filtrate is cooled and acidified with 4M hydrochloric acid. The precipitate formed is suction filtered and dried. 8.03 g of product II (75%) is obtained as a powder.