HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid → 2-[[1-Cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid | HCID 5276167 | — |
| Edukt | (2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid | HCID 6957986 | — |
| Produkt | 2-[[1-Cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid | HCID 5276198 | 36% |
Reaktionsschritte
The general procedure described for Compound 242 was used with Fmoc-Tyr Wang resin (125 mg, 0.8 mmol/g), producing 22 mg of the title compound (36% yield). MS: 610.22 (M−H+) HPLC Procedure A, retention time=16.14 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07511145B2 |
| Quelldatensatz | uspto-grants-2009_03 |
| ORD ID | ord-cb5c027e03e6415d968c993d4dbb6529 |
| Quellennotiz | uspto-grants-2009_03 |