Bromine → 2-Bromo-6-phenylcyclohexanone

HRID 1803207

Reaktionsgleichung

Reaktionsgleichung von HRID 1803207
[Br:1]Br.[C:3]1([CH:9]2[CH2:14][CH2:13][CH2:12][CH2:11][C:10]2=[O:15])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>C(Cl)(Cl)(Cl)Cl>[Br:1][CH:11]1[CH2:12][CH2:13][CH2:14][CH:9]([C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)[C:10]1=[O:15]

Komponenten

4

Edukt 2

HCID 24408BromineHCID 955922-Phenylcyclohexanone

Produkt 1

HCID 127791292-Bromo-6-phenylcyclohexanone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel2×

Versuchsvorschrift

Step AAA (1): Followed the procedure of B. Miller and H.-S. Wong Tetrahedron 1972, 28, 2369. A solution of bromine (0.348 mL, 6.75 mmol) in CCl4 (5 mL) was added dropwise to a solution of 2-phenylcyclohexanone (1.12 g, 6.43 mmol) in CCl4 (11 mL) at 0° C. The nearly colorless solution was evaporated in vacuo to afford 2-bromo-6-phenylcyclohexanone. The crude product, which is prone to decomposition, was used for subsequent chemistry without purification or characterization.

Aufarbeitung

  1. customThe nearly colorless solution was evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-69cc67a51c494efbb6ab3c227d987293
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08349880B2

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