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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1804020Erstellt: 26. Oktober 2026

6-Bromonicotinic acid → (6-Bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone

https://huagongshe.com/reaction/1804020

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt6-Bromonicotinic acidHCID 238932—
Edukt1-(3,5-Dimethylpyridin-2-yl)piperazineHCID 58484496—
Produkt(6-Bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanoneHCID 5848466199,9%

Reaktionsschritte

By reaction and treatment in the same manner as in Preparation Example 67 and using 6-bromonicotinic acid (808 mg) and 1-(3,5-dimethylpyridin-2-yl)piperazine (765 mg) described in Preparation Example 47, the title compound (1.5 g) was obtained.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08354401B2
Quelldatensatzuspto-grants-2013_01
ORD IDord-dd1fcf73389147b48bd2fc583ef2e1c4
Quellennotizuspto-grants-2013_01