HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Fluoro-4-methylpyridine-3-carboxylic acid → [4-(3,5-Dicyclopropylpyridin-2-yl)piperazin-1-yl](6-fluoro-4-methylpyridin-3-yl)methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-Fluoro-4-methylpyridine-3-carboxylic acid | HCID 46739274 | — |
| Edukt | 1-(3,5-Dicyclopropylpyridin-2-yl)piperazine | HCID 58484701 | — |
| Produkt | [4-(3,5-Dicyclopropylpyridin-2-yl)piperazin-1-yl](6-fluoro-4-methylpyridin-3-yl)methanone | HCID 58484583 | 85,3% |
Reaktionsschritte
By reaction and treatment in the same manner as in Preparation Example 60 and using 6-fluoro-4-methylnicotinic acid (600 mg) and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine (922 mg) described in Preparation Example 62, the title compound (1.23 g) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08354401B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-32fe52f8662941c7a606f93d7c255c3d |
| Quellennotiz | uspto-grants-2013_01 |