HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Bromo-2-cyanobenzoic acid → 5-Bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Bromo-2-cyanobenzoic acid | HCID 58484585 | — |
| Edukt | 1-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine | HCID 58484718 | — |
| Produkt | 5-Bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile | HCID 58484573 | 82,2% |
Reaktionsschritte
By reaction and treatment in the same manner as in Preparation Example 90 and using 4-bromo-2-cyanobenzoic acid (2.14 g) described in Preparation Example 192 and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine (2.16 g) described in Preparation Example 96, the title compound (3.31 g) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08354401B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-ccd4a5f4a40347b58662aa1b29afc40b |
| Quellennotiz | uspto-grants-2013_01 |