Hydrochloric Acid → Rac-(2r,3r,4r,5s)-3-(3-chloro-phenyl)-4-(4-chloro-phenyl)-4-cyano-5-isopropyl-pyrrolidine-2-carboxylic acid((s)-3,4-dihydroxy-butyl)-amide

Reaktionsgleichung

FC(F)(F)C(O)=O.[Cl:8][C:9]1[CH:10]=[C:11]([CH:15]2[C:19]([C:22]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=3)([C:20]#[N:21])[CH:18]([CH:29]([CH3:31])[CH3:30])[NH:17][CH:16]2[C:32](O)=[O:33])[CH:12]=[CH:13][CH:14]=1.CC1(C)[O:40][C@@H:39]([CH2:41][CH2:42][NH2:43])[CH2:38][O:37]1.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.Cl>C(Cl)Cl.O1CCCC1>[OH:40][C@H:39]([CH2:38][OH:37])[CH2:41][CH2:42][NH:43][C:32]([CH:16]1[CH:15]([C:11]2[CH:12]=[CH:13][CH:14]=[C:9]([Cl:8])[CH:10]=2)[C:19]([C:22]2[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=2)([C:20]#[N:21])[CH:18]([CH:29]([CH3:30])[CH3:31])[NH:17]1)=[O:33]