Hydrochloric Acid → rac-(2R,3S,4R,5S)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2-cyclopropyl-2-methyl-propyl)-pyrrolidine-2-carboxylic acid ((S)-3,4-dihydroxy-butyl)-amide

Reaktionsgleichung

[Cl:1][C:2]1[C:3]([F:33])=[C:4]([CH:8]2[C:12]([C:15]3[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:16]=3[F:22])([C:13]#[N:14])[CH:11]([CH2:23][C:24]([CH:27]3[CH2:29][CH2:28]3)([CH3:26])[CH3:25])[NH:10][CH:9]2[C:30](O)=[O:31])[CH:5]=[CH:6][CH:7]=1.CC1(C)[O:39][C@@H:38]([CH2:40][CH2:41][NH2:42])[CH2:37][O:36]1.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.Cl>C(Cl)Cl.O1CCCC1>[OH:39][C@H:38]([CH2:37][OH:36])[CH2:40][CH2:41][NH:42][C:30]([CH:9]1[CH:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[C:3]=2[F:33])[C:12]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:16]=2[F:22])([C:13]#[N:14])[CH:11]([CH2:23][C:24]([CH:27]2[CH2:28][CH2:29]2)([CH3:25])[CH3:26])[NH:10]1)=[O:31]