Hydrochloric Acid → rac-(2R,3S,4R,5S)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-[2-methyl-2-(5-methyl-furan-2-yl)-propyl]-pyrrolidine-2-carboxylic acid ((S)-3,4-dihydroxy-butyl)-amide

Reaktionsgleichung

FC(F)(F)C(O)=O.[Cl:8][C:9]1[C:10]([F:43])=[C:11]([CH:15]2[C:19]([C:22]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:23]=3[F:29])([C:20]#[N:21])[CH:18]([CH2:30][C:31]([CH3:39])([C:33]3[O:34][C:35]([CH3:38])=[CH:36][CH:37]=3)[CH3:32])[NH:17][CH:16]2[C:40](O)=[O:41])[CH:12]=[CH:13][CH:14]=1.CC1(C)[O:49][C@@H:48]([CH2:50][CH2:51][NH2:52])[CH2:47][O:46]1.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.Cl>C(Cl)Cl.O1CCCC1>[OH:49][C@H:48]([CH2:47][OH:46])[CH2:50][CH2:51][NH:52][C:40]([CH:16]1[CH:15]([C:11]2[CH:12]=[CH:13][CH:14]=[C:9]([Cl:8])[C:10]=2[F:43])[C:19]([C:22]2[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:23]=2[F:29])([C:20]#[N:21])[CH:18]([CH2:30][C:31]([CH3:39])([C:33]2[O:34][C:35]([CH3:38])=[CH:36][CH:37]=2)[CH3:32])[NH:17]1)=[O:41]