Butylamine → HCID 10378649, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([NH:6][CH2:7][CH2:8][CH2:9][CH3:10])=[O:5].[CH2:15]([NH2:19])[CH2:16]CC.[C:20]12[C:26](=CC=CC=1)[NH:25]C(=O)OC2=O>>[CH2:7]([NH:6][C:4](=[O:5])[C:3]1[CH:11]=[CH:12][CH:13]=[CH:14][C:2]=1[NH:1][CH2:20][C:26]1[NH:25][CH2:16][CH2:15][N:19]=1)[CH2:8][CH2:9][CH3:10]Komponenten
4
Versuchsvorschrift
2-Amino-N-butylbenzamide (prepared from butylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give N-butyl-2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]benzamide, isolated as the hydrochloride salt.
Aufarbeitung
- customwere reacted