Ethanol → Ethyl N-cyclopentylglycinate--hydrogen chloride (1/1)

HRID 1821712

Reaktionsgleichung

Reaktionsgleichung von HRID 1821712
[CH:1]1([NH:6][CH2:7][C:8]([OH:10])=[O:9])[CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:13])=O.[CH3:15][CH2:16]O>>[ClH:13].[CH2:15]([O:9][C:8](=[O:10])[CH2:7][NH:6][CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[CH3:16]

Komponenten

4

Edukt 3

HCID 702EthanolHCID 24386Thionyl ChlorideHCID 3141012-(Cyclopentylamino)acetic acid

Produkt 1

HCID 13089663Ethyl N-cyclopentylglycinate--hydrogen chloride (1/1)

Versuchsvorschrift

Cyclopentylglycine ethyl ester hydrochloride salt was prepared by the procedure in Example 1(B) utilizing cyclopentylglycine (5.0 g, 38.7 mmol), thionyl chloride (6.0 mL, 77.4 mmol) and EtOH (34.10 mL, 58.1 mmol). The ethyl ester 14aj was obtained as a white solid (2.25 g, 10.86 mmol, 56%).

Quellen und Nachweise

ORD-Eintrag
ord-3191a0ced3354e80a1eb982961fc1c18
Quelldatensatz
uspto-grants-2009_10
Patentnummer
US07608599B2

Verknüpfte Notizen

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