4-Nitrobenzaldehyde → HCID 178477495, Verbindung

HRID 1822489Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1822489
O=Cc1ccc([N+](=O)[O-])cc1.CCSC(=O)C(OCc1ccccc1)C(=O)O>NCc1ccccc1.O=C(O)C(F)(F)F.CN(C)c1ccncc1.C1CCOC1>CCSC(=O)/C(=C/c1ccc([N+](=O)[O-])cc1)OCc1ccccc1

Komponenten

6

Edukt 2

HCID 5414-NitrobenzaldehydeHCID 178477513HCID 178477513, Verbindung

Produkt 1

HCID 178477495HCID 178477495, VerbindungAusbeute 90 %

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 142844-(Dimethylamino)pyridineReagenzHCID 12484433Benzenemethanamine, trifluoroacetateKatalysatorHCID 8028TetrahydrofuranLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Aufarbeitung

  1. temperatureThe product mixture was cooled to 25 °C.
  2. filtrationFiltered through a pad of celite · Organic-Phase beibehalten
  3. wash"The celite was washed with ethyl acetate (3 x 1 mL)."
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.

Quellen und Nachweise

ORD-Eintrag
ord-2a15c9d5f21f4683a7f7ee3bce9a6127
Quelldatensatz
Bayesian optimization of 5 decarboxylative olefination reactions

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